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Updated: Aug 14, 2026

HPLC Coupled with Chemical Fingerprinting for Multi-Pattern Recognition for Identifying the Authenticity of Clematidis Armandii Caulis
Published on: November 11, 2022
[Application of HPLC/ELSD fingerprint and constellation graphical clustering method applied to evaluate the quality
Shi-Kai Yan1, Wen-Feng Xin, Yi-Ming Wang
1Department of Chinese Medicine Science and Engineering, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, China.
Aim:
To evaluate the quality of Qingkailing injections effectively, and to develop a credible method for the quality control of traditional Chinese medicine.
Methods:
Fingerprints of 18 Qingkailing injection samples from various manufacturers were obtained by HPLC/ELSD, and quality evaluation was performed by constellation graphical clustering method.
Results:
HPLC/ELSD and constellation graphical clustering method properly revealed the quality information apparently and accurately.
Conclusion:
It was an apparent, credible and efficient method for quality evaluation of Chinese medicines.
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