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Updated: Aug 14, 2026

Microfluidics in Assessing Platelet Function
Published on: November 8, 2024
Optimal antiplatelet treatment for percutaneous coronary intervention: clopidogrel vs. ticlopidine
Abstract:
Antiplatelet treatment for patients undergoing percutaneous coronary interventions is a rapidly changing area. Thienopyridines derivatives (ticlopidine and clopidogrel) have shown to decrease major cardiovascular events. Ticlopidine can cause rare but serious side effects, especially during the first 3 months of treatment. Clopidogrel appears to be a safer alternative to ticlopidine. However, resistance to clopidogrel therapy may increases the risk of recurrent cardiovascular events. Whether increased doses of clopidogrel might overcome this resistance in nonresponsive patients warrants further investigation.
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