Related Experiment Video
Updated: Aug 14, 2026

Production and Purification of Baculovirus for Gene Therapy Application
Published on: April 9, 2018
Envelope gene capture and insect retrovirus evolution: the relationship between errantivirus and baculovirus envelope
Margot N Pearson1, George F Rohrmann
1Department of Microbiology, Oregon State University Corvallis, 97331-3804, USA.
Abstract:
In this report the evolution of insect retroviruses (errantiviruses) is reviewed with particular emphasis on the relationship between their env protein and a baculovirus envelope fusion protein. In addition, selected features of the env protein from the errantivirus Dme17.6V are examined. These include characterization of the 21 amino acid predicted fusion peptide sequence that is highly homologous to a region of baculovirus envelope fusion proteins. We found that, although this sequence could not substitute for the homologous sequence in the baculovirus LD130 envelope fusion protein, by changing four amino acids, the hybrid construct became active for low-pH induced cell fusion. In addition, a Dme17.6V env-egfp construct was found to localize to cell membranes.
More Related Videos
12:20Bacterial Artificial Chromosomes: A Functional Genomics Tool for the Study of Positive-strand RNA Viruses
Published on: December 29, 2015
08:10Production of High-Titer Infectious Influenza Pseudotyped Particles with Envelope Glycoproteins from Highly Pathogenic H5N1 and Avian H7N9 Viruses
Published on: January 15, 2020
Related Concept Videos
Retroviruses
Retrovirus Life Cycles
LTR Retrotransposons
The internal coding region of LTR retrotransposons and their mechanism of transposition closely resembles a...
Introduction to Virus
Viral Recombination
Non-LTR Retrotransposons