Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Factors controlling neural activity during delayed-response task performance: testing a memory organization

B Rypma1

  • 1Rutgers University, Psychology Department, Smith Hall, 101 Warren Street, Newark, NJ 07102, USA. rypma@psychology.rutgers.edu

Neuroscience
|December 14, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Baseline cerebral metabolism predicts fatigue and cognition in Multiple Sclerosis patients.

NeuroImage. Clinical·2020
Same author

Age differences in prefrontal cortical activity in working memory.

Psychology and aging·2001
Same author

Neural substrates of mathematical reasoning: a functional magnetic resonance imaging study of neocortical activation during performance of the necessary arithmetic operations test.

Neuropsychology·2001
Same author

Prefrontal cortical contributions to working memory: evidence from event-related fMRI studies.

Experimental brain research·2000
Same author

Isolating the neural mechanisms of age-related changes in human working memory.

Nature neuroscience·2000
Same author

Imagined transformations of bodies: an fMRI investigation.

Neuropsychologia·1999

The prefrontal cortex

Area of Science:

  • Neuroscience
  • Cognitive Neuroscience

Background:

  • Prefrontal cortex (PFC) function is crucial for cognitive tasks.
  • Delayed-response tasks are widely used to study PFC roles.

Purpose of the Study:

  • To review neuroimaging findings on PFC activity during delayed-response tasks.
  • To evaluate the 'memory-organization hypothesis' of PFC function.
  • To explore how task structure influences neural variability.

Main Methods:

  • Review of existing neuroimaging literature.
  • Analysis of memory-load-related PFC activity.
  • Examination of empirical support for the memory-organization hypothesis.

Main Results:

  • Consistent PFC activity linked to memory load supports the memory-organization hypothesis.

Related Experiment Videos

  • Task structure variations yield meaningful neuroimaging data variability.
  • Between-study variance in neural activity locus and timing offers insights.

    • Conclusions:

    • The memory-organization hypothesis provides a framework for PFC function in delayed response tasks.
    • Subtle task-structure manipulations are key to understanding PFC strategy variations.
    • Future research should systematically manipulate task variables to refine PFC role understanding.