Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Factor VII inhibitor.

J Mehta¹, S Singhal, B C Mehta

¹Blood Research Centre, Bombay.

The Journal of the Association of Physicians of India

|January 1, 1992

Summary

This summary is machine-generated.

A rare acquired factor VII inhibitor developed in a patient, potentially due to penicillin. This inhibitor led to fatal bleeding, highlighting a critical complication of drug-induced coagulation disorders.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Prevalence of hematinics deficiency amongst female students and its correction.

Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion·2012

Same author

Hyperammonemia: an unusual presenting feature of multiple myeloma.

Indian journal of medical sciences·2005

Same author

Iron deficiency amongst nursing students.

Indian journal of medical sciences·2004

Same author

Approach to a patient with anemia.

Indian journal of medical sciences·2004

Same author

Dr. Jamnadas C. Patel.

Indian journal of medical sciences·2003

Same author

NESTROFT: a screening test for beta thalassemia trait.

Indian journal of medical sciences·2003

Same journal

Indian Expert Consensus on Allergic Rhinitis in Women: A Modified Delphi Survey.

The Journal of the Association of Physicians of India·2026

Same journal

Systematic Review of Topical Capsaicin 0.075% for the Treatment of Neuropathic Pain: Efficacy, Safety, and Tolerability.

The Journal of the Association of Physicians of India·2026

Same journal

Sodium-Glucose Cotransporter 2 Inhibitors in Kidney Diseases Other Than That Due to Diabetes: Benefits in Composite Renal Outcomes Driven by Immunoglobulin A Nephropathy.

The Journal of the Association of Physicians of India·2026

Same journal

<i>Fasciolopsis buski</i> Diagnosed by Upper Gastrointestinal Endoscopy.

The Journal of the Association of Physicians of India·2026

Same journal

"Academic Overdose" among Healthcare Professionals.

The Journal of the Association of Physicians of India·2026

Same journal

Respiratory Examination for Postgraduate Residents: Unrevealing Expert's Questions and Answers.

The Journal of the Association of Physicians of India·2026

See all related articles

Area of Science:

Hematology
Pharmacology
Internal Medicine

Background:

Acquired inhibitors of blood coagulation factors are uncommon, arising spontaneously or secondary to diseases or medications.
Clinically significant inhibitors targeting factor VII are exceptionally rare in medical literature.

Observation:

This report details a patient who developed an acquired factor VII inhibitor.
The inhibitor's onset was possibly linked to penicillin administration.

Findings:

The patient's factor VII inhibitor led to severe, fatal hemorrhage.
This case underscores the potential for drug-induced immune responses to disrupt hemostasis.

Implications:

Highlights the importance of considering drug reactions in acquired coagulation factor deficiencies.

Related Experiment Videos

Emphasizes the critical and potentially fatal consequences of rare inhibitor development.

Suggests vigilance for coagulation abnormalities in patients receiving certain medications.