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Nocturnal enuresis and psychosocial problems in pediatric sickle cell disease and sibling controls
Sara Sytsma Jordan1, Kellie A Hilker, Laura Stoppelbein
1Department of Psychology, University of Southern Mississippi, Hattiesburg 39406-5025, USA. Sara.Jordan@usm.edu
Insights
Children with sickle cell disease (SCD) experience higher rates of nocturnal enuresis and associated psychosocial problems compared to siblings. Early screening and intervention are crucial for managing these conditions in children with SCD.
Area of Science:
- Pediatric Hematology
- Child Psychology
- Clinical Epidemiology
Background:
- Nocturnal enuresis and psychosocial issues are common in children.
- Sickle cell disease (SCD) may impact these conditions, but data is limited.
- Understanding these comorbidities is vital for comprehensive care.
Purpose of the Study:
- To compare prevalence rates of nocturnal enuresis and psychosocial problems in children with SCD versus sibling controls.
- To investigate the relationship between enuresis and psychosocial difficulties in children with SCD.
- To provide evidence for improved clinical monitoring and treatment strategies.
Main Methods:
- A structured interview and the Pediatric Symptom Checklist were used.
- Data collected from primary caretakers of 126 children with SCD (ages 5-17) and 47 sibling controls.
- Statistical analyses controlled for child age.
Main Results:
- Lifetime enuresis rates in children with SCD exceeded population and sibling control rates.
- Enuretic children, regardless of group, showed higher total psychosocial problems.
- Psychosocial problem patterns varied by enuresis history and group status.
Conclusions:
- Children with SCD have significantly higher rates of nocturnal enuresis.
- Enuresis is linked to increased psychosocial problems in children with SCD.
- Monitoring hydration and screening for psychosocial issues in children with SCD and enuresis is recommended.
Abstract:
To evaluate current and lifetime prevalence rates of nocturnal enuresis and psychosocial problems among children with sickle cell disease (SCD) in comparison with sibling controls, a structured interview and the Pediatric Symptom Checklist were administered to primary caretakers regarding 126 of their children aged 5 to 17 with SCD and 47 sibling controls. Lifetime rates of enuresis among children with SCD were comparable to similar studies, and exceeded population prevalence and sibling control rates. In addition, enuretic children had higher levels of total psychosocial problems on the Pediatric Symptom Checklist regardless of group status, although patterns of subscale differences varied by group and enuresis history after controlling for child age. These findings replicate and extend previous findings and provide further evidence to support a need for monitoring of hydration levels and screening for psychosocial problems among children with SCD and enuresis, as well as evaluation of the psychometric properties of psychosocial screening measures and identification of efficacious treatments for enuresis in children with SCD.
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