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Nocturnal enuresis and psychosocial problems in pediatric sickle cell disease and sibling controls

Sara Sytsma Jordan1, Kellie A Hilker, Laura Stoppelbein

  • 1Department of Psychology, University of Southern Mississippi, Hattiesburg 39406-5025, USA. Sara.Jordan@usm.edu

Insights

Children with sickle cell disease (SCD) experience higher rates of nocturnal enuresis and associated psychosocial problems compared to siblings. Early screening and intervention are crucial for managing these conditions in children with SCD.

Area of Science:

  • Pediatric Hematology
  • Child Psychology
  • Clinical Epidemiology

Background:

  • Nocturnal enuresis and psychosocial issues are common in children.
  • Sickle cell disease (SCD) may impact these conditions, but data is limited.
  • Understanding these comorbidities is vital for comprehensive care.

Purpose of the Study:

  • To compare prevalence rates of nocturnal enuresis and psychosocial problems in children with SCD versus sibling controls.
  • To investigate the relationship between enuresis and psychosocial difficulties in children with SCD.
  • To provide evidence for improved clinical monitoring and treatment strategies.

Main Methods:

  • A structured interview and the Pediatric Symptom Checklist were used.
  • Data collected from primary caretakers of 126 children with SCD (ages 5-17) and 47 sibling controls.
  • Statistical analyses controlled for child age.

Main Results:

  • Lifetime enuresis rates in children with SCD exceeded population and sibling control rates.
  • Enuretic children, regardless of group, showed higher total psychosocial problems.
  • Psychosocial problem patterns varied by enuresis history and group status.

Conclusions:

  • Children with SCD have significantly higher rates of nocturnal enuresis.
  • Enuresis is linked to increased psychosocial problems in children with SCD.
  • Monitoring hydration and screening for psychosocial issues in children with SCD and enuresis is recommended.

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