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Updated: Aug 14, 2026

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
Published on: April 12, 2019
Abdominal pain in a patient with osteosarcoma
Paul T Jubinsky1, James Pullman, Netta Blitman
1Department of Pediatrics, Albert Einstein College of Medicine and Children's Hospital at Montefiore, Bronx, NY 10461, USA. pjubinsk@aecom.yu.edu
Chemotherapy can cause abdominal pain. In a patient with osteosarcoma, severe abdominal discomfort was unexpectedly caused by a pelvic mass, not treatment side effects.
Area of Science:
- Oncology
- Medical Diagnostics
Background:
- Chemotherapy is a common cancer treatment associated with various side effects.
- Abdominal pain is a frequent complaint among patients undergoing chemotherapy.
- Neutropenia and mucositis are known complications of chemotherapy.
Observation:
- A patient with osteosarcoma presented with fever, neutropenia, and mucositis.
- The patient subsequently developed severe right-sided abdominal discomfort.
- The abdominal pain was evaluated for potential chemotherapy-related causes.
Findings:
- The severe abdominal pain was not directly related to chemotherapy treatment.
- Diagnostic imaging revealed a midline pelvic mass as the cause of the patient's discomfort.
- This finding highlights the importance of considering non-therapy-related etiologies for abdominal pain in chemotherapy patients.
Implications:
- Clinicians should maintain a broad differential diagnosis for abdominal pain in patients receiving chemotherapy.
- Pelvic masses can present with abdominal pain, even in the context of chemotherapy-induced symptoms.
- Thorough diagnostic evaluation is crucial to identify the precise cause of abdominal pain and guide appropriate management.
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