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Published on: July 5, 2017
Cardiovascular fitness and physical activity in children with and without impaired glucose tolerance
G Q Shaibi1, G D C Ball, M L Cruz
1Department of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, 90033, USA.
Insights
Overweight Hispanic children with impaired glucose tolerance (IGT) show similar cardiovascular fitness (VO2max) and physical activity levels compared to those with normal glucose tolerance (NGT). Further research is needed to understand long-term diabetes risk in this population.
Area of Science:
- Pediatric Endocrinology
- Cardiovascular Health
- Metabolic Health
Background:
- Overweight Hispanic children are at increased risk for type 2 diabetes.
- Understanding factors influencing glucose tolerance in this demographic is crucial.
Purpose of the Study:
- To compare cardiovascular fitness (VO2max) and physical activity levels between overweight Hispanic children with normal glucose tolerance (NGT) and impaired glucose tolerance (IGT).
Main Methods:
- 173 overweight Hispanic children (ages 8-13) with a family history of type 2 diabetes were studied.
- Cardiovascular fitness was assessed using maximal treadmill tests (VO2max).
- Physical activity was measured via questionnaire, and glucose tolerance was determined through an oral glucose challenge test.
Main Results:
- Approximately 27% of participants had impaired glucose tolerance (IGT).
- No significant differences in absolute or adjusted VO2max were found between NGT and IGT groups.
- Recreational physical activity levels did not differ significantly between the NGT and IGT groups.
Conclusions:
- Overweight Hispanic youth with IGT demonstrate comparable VO2max and physical activity levels to their NGT peers.
- Longitudinal studies are required to ascertain the predictive value of fitness and activity on diabetes risk in this cohort.
Objective:
To examine differences in cardiovascular fitness (VO(2max)) and physical activity levels in overweight Hispanic children with normal glucose tolerance (NGT) vs impaired glucose tolerance (IGT).
Participants:
A total of 173 overweight (BMI percentile 97.0 +/- 3.1) Hispanic children ages 8-13 years with a family history of type 2 diabetes.
Methods:
VO(2max) was measured via a maximal effort treadmill test and open circuit spirometry. Physical activity was determined by questionnaire. Glucose tolerance was established by a 2-h oral glucose challenge (1.75 g of glucose/kg body weight). IGT was defined from an oral glucose tolerance test as a 2-h plasma glucose level > or =140 and <200 mg/dl.
Results:
IGT was detected in 46 of the 173 participants (approximately 27%); no cases of type 2 diabetes were identified. No significant differences were found between youth with NGT and those with IGT in absolute VO(2max) (2.2 +/- 0.6 vs 2.1 +/- 0.5 l/min), VO(2max) adjusted for gender, age, and body composition (2.2 +/- 0.2 vs 2.1 +/- 0.2 l/min), or recreational physical activity levels (8.7 +/- 8.2 vs 6.9 +/- 6.2 h/week).
Conclusion:
Overweight Hispanic youth with IGT exhibit similar levels of VO(2max) and physical activity compared to their NGT counterparts. Longitudinal analyses are necessary to determine whether fitness/activity measures contribute significantly to diabetes risk over time in this group.
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