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Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues
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Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues

Published on: July 14, 2015

[Evaluation of intramolecular interaction between complementary domains, connected with a flexible chain]

S A Bobrovnik, F J Stevens

    Ukrains'Kyi Biokhimichnyi Zhurnal (1999 )
    |December 15, 2005
    PubMed
    Summary

    This study introduces a method to calculate effective binding parameters for flexible chain-linked domains. It reveals that constrained domains can form complexes at higher fractional contents than expected from absolute concentrations.

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