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Published on: December 15, 2011
Unusual presentation of IgA nephropathy in childhood: a case report
Nurcan Cengiz1, Esra Baskin, Pinar Isik Agras
1Department of Pediatric Nephrology, Baskent University Faculty of Medicine, Ankara, Turkey. nurcem@yahoo.com
Abstract:
Immunoglobulin A (IgA) nephropathy is the most common form of primary glomerulonephritis worldwide, and approximately 20% to 30% of adult patients with the disorder develop chronic renal failure within 20 years. This type of nephropathy is also an important risk factor for chronic renal failure in children. The pathogenesis of IgA nephropathy is still unknown, and treatment remains controversial. Microscopic hematuria and recurrent episodes of macroscopic hematuria are the most common clinical manifestations of this condition in children. This article describes the case of a young girl who presented with steroid-resistant nephrotic syndrome unaccompanied by hematuria. Renal biopsy findings were consistent with IgA nephropathy. The patient's condition was a rare clinical manifestation of IgA nephropathy.
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