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Updated: Jul 15, 2026

Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles
Published on: May 8, 2015
Self-assembly of DNA double-double crossover complexes into high-density, doubly connected, planar structures
Dustin Reishus1, Bilal Shaw, Yuriy Brun
1Laboratory for Molecular Science, University of Southern California, Los Angeles, California 90089-2910, USA.
Abstract:
We designed a molecular complex, the double-double crossover, consisting of four DNA double helices connected by six reciprocal exchanges. Atomic force micrographs suggest that double-double crossover complexes self-assemble into high-density, doubly connected, two-dimensional, planar structures. Such structures may be suitable as substrates for the deposition of nanomaterials in the creation of high-density electrical and quantum devices. We speculate about a modified double-double crossover complex that might self-assemble into high-density, doubly connected, three-dimensional structures.
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