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Updated: Aug 1, 2026

Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles
Published on: August 28, 2015
Simultaneous, segregated storage of two agents in a multicompartment micelle
Timothy P Lodge1, April Rasdal, Zhibo Li
1Department of Chemistry, University of Minnesota, 207 Pleasant Street SE, Minneapolis, Minnesota 55455-0431, USA. lodge@chem.umn.edu
Abstract:
The simultaneous, segregated storage of two different chromophores in a multicompartment micelle, which is formed from self-assembly of (polyethylethylene)(polyethylene oxide)(polyperfluoropropylene oxide) mikto-arm star terpolymers in water, was investigated by spectrophotometry. The multicompartment micelles, with segregated micellar cores composed of fluorocarbon and hydrocarbon compartments, can simultaneously absorb two chemically different molecules. These two molecules were confined into their preferred compartments with high selectivity.
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