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[Herpetic encephalitis in adults: 23 cases].
F J Burón Mediavilla1, J C Rodríguez Borregán, E Miñambres
1Servicio de Medicina Intensiva, Hospital Universitario Marqués de Valdecilla, Santander. fjburon@humv.es
Anales De Medicina Interna (Madrid, Spain : 1984)
|December 15, 2005
Summary
Herpetic encephalitis is uncommon but serious. Early intravenous acyclovir treatment improves prognosis, as delayed care worsens outcomes and functional independence is rarely achieved.
Area of Science:
- Neurology
- Infectious Diseases
Context:
- Herpetic encephalitis is a rare but severe neurological condition.
- This study analyzes 23 adult cases over 12 years.
Purpose:
- To investigate the clinical presentation, diagnosis, treatment, and prognosis of herpetic encephalitis.
- To evaluate the effectiveness of intravenous acyclovir and the role of corticosteroids.
Summary:
- Common symptoms include decreased consciousness and fever.
- Cerebrospinal fluid analysis frequently shows lymphocytic pleocytosis.
- Temporal lobe lesions on CT scans were observed in 61% of patients.
Impact:
- Intravenous acyclovir is the recommended treatment; corticosteroid use is debated.
- Delayed treatment initiation significantly worsens patient prognosis.
- Less than one-third of patients achieve functional independence upon hospital discharge.
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