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Related Experiment Videos

Thrombus on an ASD closure device: a call for caution.

J C Cooke1, J S Gelman, S Menahem

  • 1Centre for Heart and Chest Research, Monash Medical Centre, Clayton, Victoria, Australia. jennifer_cooke@yahoo.com

Heart, Lung & Circulation
|December 15, 2005
PubMed
Summary

Atrial septal defect closure devices are common, but a case report shows left atrial thrombus formation on a StarFLEX device. This raises concerns about device safety and preventing paradoxical embolism.

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Area of Science:

  • Cardiology
  • Medical Devices
  • Interventional Cardiology

Background:

  • Per-catheter closure of atrial septal defects (ASDs) is a growing interventional cardiology procedure.
  • Various devices are available for ASD closure, each with unique designs and potential complications.
  • Ensuring device safety and efficacy, particularly regarding thromboembolic events, is crucial.

Purpose of the Study:

  • To report a case of left atrial thrombus formation on a specific per-catheter ASD closure device.
  • To discuss the implications of this complication for the broader use of such devices.
  • To evaluate the role of these devices in preventing paradoxical embolism.

Main Methods:

  • Case report detailing a patient who developed a complication after ASD device closure.

Related Experiment Videos

  • Review of relevant literature on atrial septal defect closure devices and thrombus formation.
  • Analysis of the specific device used and potential contributing factors.

    • Main Results:

    • A left atrial thrombus was identified on the StarFLEX device post-implantation.
    • The presence of the thrombus raises concerns about the thrombogenicity of the device.
    • This finding questions the universal applicability of these devices for preventing paradoxical embolism.

    Conclusions:

    • Left atrial thrombus formation is a potential complication associated with per-catheter ASD closure devices.
    • The StarFLEX device, in this case, was associated with thrombus formation, necessitating further investigation.
    • The findings highlight the need for careful patient selection and monitoring to mitigate risks like paradoxical embolism.