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Coffee and coronary heart disease.
O B Tofler1, S Foy, K Ng
1Cardiology Department and Coronary Care Unit, Royal Perth Hospital Perth, Western Australia, Australia.
Heart, Lung & Circulation
|December 15, 2005
Summary
Drinking more than five cups of coffee daily may increase the risk of myocardial infarction (MI) and unstable angina. This case-control study suggests a significant association between high coffee consumption and acute coronary syndromes.
Area of Science:
- Cardiology
- Epidemiology
- Nutritional Science
Background:
- The association between coffee consumption and myocardial infarction (MI) risk is debated.
- Cohort studies show minimal risk, while case-control studies suggest a ~60% increase for high intake.
Purpose of the Study:
- To investigate the relationship between coffee consumption and acute coronary syndromes.
- To determine if high coffee intake is a risk factor for myocardial infarction or unstable angina.
Main Methods:
- A case-control study was conducted at Royal Perth Hospital, Australia.
- Lifestyle and coffee consumption data were collected via questionnaires from patients admitted with chest pain and those attending a cardiology clinic.
- Data included 182 patients with acute coronary syndromes and 185 with chronic stable coronary heart disease.
Main Results:
- Patients with acute coronary syndromes (myocardial infarction or unstable angina) consumed more than five cups of coffee daily compared to those with chronic stable coronary heart disease (18% vs 7.5%, P=0.003).
- Adjusted logistic regression revealed an odds ratio of 2.51 (95% CI 1.43-4.43, P=0.021) for acute coronary syndromes associated with high coffee intake.
Conclusions:
- This case-control study indicates that consuming over five cups of coffee per day is associated with an increased risk of myocardial infarction or unstable angina.