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Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
No decrease in incidence of atrial fibrillation in patients undergoing off-pump coronary artery bypass grafting
Silvana F Marasco1, John Goldblatt, Michael McDonald
1Cardiothoracic Unit, Royal Melbourne Hospital, Parkville, Victoria, Australia. silvanamarasco@hotmail.com
Off-pump coronary artery bypass grafting (CABG) did not reduce the incidence of postoperative atrial fibrillation (AF) compared to traditional CABG with cardiopulmonary bypass. Age was a risk factor, while beta-blockade was protective.
Area of Science:
- Cardiology
- Cardiac Surgery
- Electrophysiology
Background:
- Beating heart surgery, specifically off-pump coronary artery bypass grafting (CABG), has prompted interest in its effect on postoperative atrial fibrillation (AF).
- Previous studies suggested lower AF rates with off-pump CABG, necessitating further investigation.
Purpose of the Study:
- To evaluate the incidence of postoperative atrial fibrillation (AF) in patients undergoing off-pump CABG.
- To compare AF rates between off-pump CABG and conventional CABG with cardiopulmonary bypass (CPB).
Main Methods:
- A retrospective review of 80 patients undergoing elective first-time off-pump CABG was conducted over 16 months.
- These patients were matched with 80 patients who underwent CABG with CPB.
- Preoperative, operative variables, and postoperative AF incidence were recorded for both groups.
Main Results:
- The incidence of postoperative AF was 34% (27/80) in the off-pump CABG group and 31% (25/80) in the CPB group (not significant).
- Advanced age was identified as a significant risk factor for developing postoperative AF.
- Beta-blockade therapy demonstrated a protective effect against postoperative AF.
Conclusions:
- Off-pump CABG does not appear to decrease the incidence of postoperative atrial fibrillation compared to CABG with CPB.
- A randomized prospective trial is underway to further explore postoperative outcomes of off-pump CABG.
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