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Updated: Aug 14, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Surgical treatment of atrial fibrillation
1Division of Cardiothoracic Surgery, University of Utah School of Medicine, LDS Hospital, 324 Tenth Avenue, Salt Lake City, UT 84103, USA. ldddoty@ihc.com
Insights
Surgical treatment for atrial fibrillation, including the Cox-Maze III procedure, offers excellent results. Modified, less complex operations also restore normal heart rhythm in about 80% of patients.
Area of Science:
- Cardiology
- Cardiac Surgery
Background:
- Atrial fibrillation (AF) is a common arrhythmia requiring effective treatment strategies.
- Surgical interventions have evolved to address the complexities of AF management.
Purpose of the Study:
- To review the fundamentals of surgical treatment for atrial fibrillation.
- To discuss the evolution and efficacy of Maze procedures and their modifications.
Main Methods:
- Review of the Cox-Maze III procedure and its historical development.
- Analysis of various energy sources and techniques used in modified Maze operations.
- Evaluation of clinical outcomes and success rates of different surgical approaches.
Main Results:
- The Cox-Maze III procedure achieves excellent outcomes, with over 90% of patients achieving normal sinus rhythm.
- Modified Maze operations simplify the procedure and offer approximately 80% restoration of sinus rhythm.
- Reduced complexity and operative time make modified procedures attractive to surgeons.
Conclusions:
- Surgical treatment, particularly the Maze procedure and its modifications, is highly effective for managing atrial fibrillation.
- Ongoing innovations aim to improve efficacy and reduce the complexity of surgical AF ablation.
Abstract:
This article reviews the fundamentals of surgical treatment of atrial fibrillation. The clinical classification, pathophysiology, medical treatment strategy, and catheter-based interventions are also included. The Cox-Maze III procedure was developed over based on experiences of several operations which proceeded it. The operation is complex but results are excellent with over 90% of patients in normal sinus rhythm or regular atrial rhythm. Several modifications have been devised using various energies to ablate atrial myocardium as a means of extending surgical incisions to simplify the Maze III operation. Techniques and results of these operations are reviewed. Modified operations offering about 80% restoration of sinus rhythm are attractive to more surgeons because of the reduced complexity and time of operation.
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