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Updated: Aug 14, 2026

Hydrogen Production and Utilization in a Membrane Reactor
Published on: March 10, 2023
In situ generation of HCN for mass spectrometric studies
Silvi A Chacko1, Ian H Krouse1, Loubna A Hammad1
1Department of Chemistry, Purdue University, 560 Oval Drive, 47907-2084, West Lafayette, IN, USA.
Abstract:
Hydrogen cyanide (HCN) for use in ion preparation can be generated in the gas phase by the neutral-neutral reaction of trimethylsilyl cyanide (Me(3)SiCN) and water in a flowing afterglow mass spectrometer. We demonstrate that the approach can be used to generate a wide range of HCN solvated ions such as F(-)(HCN), Cl(-)(HCN), CN(-)(HCN), PhNO(2)(.-)(HCN), Me(3)SiO(-)(HCN),and PhSiF(4)(-)(HCN), many of which are otherwise difficult to generate. The bond dissociation energy of CN(-)(HCN), generated by using this approach, has been measured by using energy-resolved collision-induced issociation (CID) to be 0.87 +/- 0.07 eV.
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