Tissue Doppler echocardiographic identification of ischemic etiology in patients with dilated cardiomyopathy
Michał Plewka1, Maria Krzemińska-Pakuła, Jarosław Drozdz
1II Chair and Department of Cardiology, Medical University of Lodz, Bieganski Hospital, Kniaziewicza 115, 9A-347 Lodz, Poland. plewka@ptkardio.pl
Insights
Tissue Doppler echocardiography (TDE) can differentiate between ischemic and nonischemic cardiomyopathy. The dispersion index of systolic velocities is significantly higher in ischemic cardiomyopathy patients, aiding diagnosis.
Area of Science:
- Cardiology
- Echocardiography
- Cardiomyopathy Research
Background:
- Left ventricular dysfunction is a hallmark of cardiomyopathy.
- Distinguishing between ischemic and nonischemic etiologies is crucial for appropriate treatment.
Purpose of the Study:
- To compare left ventricular function in patients with ischemic and nonischemic cardiomyopathy.
- To evaluate the utility of tissue Doppler echocardiography (TDE) in differentiating these conditions.
Main Methods:
- Studied 30 patients post-myocardial infarction (MI group), 30 with dilated cardiomyopathy (DCM group), and 60 controls.
- Measured TDE velocities and cardiac cycle time intervals.
- Calculated the dispersion index of TDE parameters.
Main Results:
- Early diastolic velocities were lower in the MI group compared to the DCM group.
- The dispersion index of systolic velocities was significantly higher in the MI group than in the DCM group and controls (33.1+/-6.0% vs 12.6+/-3.7% vs 15.9+/-5.6%, p < 0.001).
- Preejection period was shorter, and isovolumic relaxation and diastasis times were longer in the MI group versus the DCM group.
Conclusions:
- TDE parameters, including early diastolic velocity and the dispersion index of systolic velocities, effectively differentiate between ischemic and nonischemic dilated cardiomyopathy.
- Specific TDE parameters can distinguish the etiology of cardiomyopathy, guiding clinical management.
Objective:
To compare the left ventricular function in patients with ischemic and nonischemic cardiomyopathy using tissue Doppler echocardiography (TDE).
Methods:
We studied 30 patients after myocardial infarction (MI group), 30 patients with dilated cardiomyopathy (DCM group) and 60 healthy volunteers in corresponding control groups. TDE velocities, time intervals of cardiac cycle were measured and dispersion index of TDE parameters was calculated.
Results:
Early diastolic velocities were lower in MI group than in DCM group, with similar systolic and late diastolic velocities. The dispersion index of systolic velocities was significantly higher in MI than in DCM group and in controls (respectively 33.1+/-6.0% vs 12.6+/-3.7% vs 15.9+/-5.6%; p < 0.001) and differentiated ischemic from idiopathic dilated cardiomyopathy. In MI group, preejection period was shorter and isovolumic relaxation and diastasis time were longer than in DCM group, with no differences in dispersion index of time intervals between the groups.
Conclusions:
TDE parameters: early diastolic velocity, preejection period, isovolumic relaxation time and the dispersion index of systolic velocities differentiate ischemic and nonischemic etiology of dilated cardiomyopathy.
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