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Antithrombotic- and anticoagulation regimens in OPCAB surgery. A Nordic survey

Katrine H Hansen1, Pia Hughes, Daniel A Steinbrüchel

  • 1Department of Cardiothoracic Surgery, H:S Rigshospitalet, Copenhagen University Hospital, Denmark. katrineha3@m1.stud.ku.dk

Scandinavian Cardiovascular Journal : SCJ
|December 15, 2005
PubMed

Insights

Practices for antiplatelet and heparin therapy in Off-Pump Coronary Artery Bypass (OPCAB) surgery vary widely across Nordic countries. Standardized protocols for antiplatelet and heparin use in OPCAB surgery are not yet established.

Area of Science:

  • Cardiothoracic Surgery
  • Cardiovascular Research
  • Anesthesiology

Background:

  • Off-Pump Coronary Artery Bypass (OPCAB) surgery is performed in the Nordic countries.
  • Current practices for perioperative antiplatelet and heparin therapy in OPCAB surgery are not well-defined.

Purpose of the Study:

  • To determine current practices for antiplatelet and heparin therapy in OPCAB surgery.
  • To identify variations in therapeutic approaches across Nordic countries.

Main Methods:

  • A 100% response rate postal survey was conducted.
  • The survey targeted all 26 Cardiothoracic Surgery departments in Norway, Sweden, Iceland, Finland, and Denmark.
  • Data on antiplatelet and heparin therapy in OPCAB procedures were collected.

Main Results:

  • 48% of departments used preoperative antiplatelet therapy; 96% used postoperative therapy.
  • Postoperative therapy showed a trend towards aspirin and low molecular weight heparin.
  • Heparin anticoagulation and protamine reversal practices varied significantly.
  • 80% of respondents reported registering postoperative complications.

Conclusions:

  • There is no uniform practice for antiplatelet and heparin therapy in OPCAB surgery in the Nordic countries.
  • Dose regimens for these therapies are highly variable.
  • Standardized protocols for perioperative management in OPCAB surgery have not been developed.
Abstract

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