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Intraocular choristoma.

Bong Hyun Kim1, Bonnie A Henderson

  • 1Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA. Bong_Kim@meei.harvard.edu

Seminars in Ophthalmology
|December 15, 2005
PubMed
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Intraocular choristomas, rare eye tumors, commonly affect the iris, ciliary body, choroid, and optic nerve head. While often benign, they can impact vision, requiring observation or surgical intervention.

Area of Science:

  • Ophthalmology
  • Ocular Oncology
  • Pathology

Background:

  • Choristomas are congenital tumors composed of tissue elements not normally found at the site of occurrence.
  • While epibulbar choristomas are well-documented, intraocular choristomas remain less understood.
  • These benign growths can arise in various intraocular structures.

Purpose of the Study:

  • To review and summarize existing literature on intraocular choristomas.
  • To elucidate the common locations, presentations, and clinical courses of these tumors.
  • To provide insights into the management of intraocular choristomas.

Main Methods:

  • Comprehensive literature search for case reports and reviews of intraocular choristomas.
  • Analysis of reported cases focusing on affected tissues, clinical presentation, and outcomes.

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  • Synthesis of findings to describe the characteristics and management of intraocular choristomas.
  • Main Results:

    • Intraocular choristomas frequently occur in the iris, ciliary body, choroid, and optic nerve head.
    • Ectopic lacrimal gland choristomas in the anterior uvea present as nodular masses, often with cysts.
    • Osseous choristomas are noted in the choroid, particularly in young females, and can exhibit progressive growth.

    Conclusions:

    • Intraocular choristomas, though generally benign, necessitate careful monitoring due to potential visual impairment.
    • Management strategies range from observation to surgical intervention, tailored to individual cases.
    • Most intraocular choristomas do not require aggressive treatment, emphasizing a conservative approach.