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Published on: November 20, 2015
Developmental delay at 12 months in children born extremely preterm
Ane Lando1, Anja Klamer, Finn Jonsbo
1Department of Neonatology, Juliane Marie Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark. alando@dadlnet.dk
Insights
A telephone questionnaire effectively assesses neurodevelopmental deficits in extremely preterm infants. This structured tool, the Revised Prescreening Developmental Questionnaire (R-PDQ), proved feasible and valid for early developmental screening.
Area of Science:
- Neonatal care and developmental pediatrics.
- Pediatric neurodevelopmental assessment.
Background:
- Extremely preterm infants (<28 weeks gestation) face risks for neurodevelopmental deficits.
- Early and accurate assessment is crucial for timely intervention.
Purpose of the Study:
- To determine the feasibility and validity of a structured telephone interview for assessing neurodevelopment in extremely preterm infants.
- To compare developmental scores between extremely preterm infants and those born at term.
Main Methods:
- Parents of 88 extremely preterm infants and 30 term infants were interviewed via telephone at 1 year corrected age using the Revised Prescreening Developmental Questionnaire (R-PDQ).
- NICU staff conducted the interviews.
- The R-PDQ's validity was further assessed by comparing its scores with the Ages and Stages Questionnaire (ASQ) at 3-3.5 years.
Main Results:
- The R-PDQ was user-friendly for staff and well-received by parents.
- Extremely preterm infants scored significantly lower on the R-PDQ (14.9±3.9) compared to term infants (17.7±2.7), indicating developmental delay.
- R-PDQ scores correlated with ASQ scores obtained two years later.
Conclusions:
- A structured telephone questionnaire is a viable and usable method for screening neurodevelopmental deficits in extremely preterm children.
- The observed mean developmental delay in the preterm group aligns with expected outcomes.
Aim:
To evaluate the feasibility and validity of a structured telephone interview to assess the development of children born extremely preterm.
Methods:
The parents of 88 children born with a gestational age below 28 wk admitted to the neonatal intensive care unit (NICU) at Rigshospitalet, Copenhagen, were interviewed by telephone when their child was 1 y of age, corrected for preterm birth. A fully structured questionnaire on psychomotor function was used (Revised Prescreening Developmental Questionnaire (R-PDQ)). The parents of 30 children born at term without complications were interviewed for comparison. The interview was conducted by NICU staff. To validate the R-PDQ, parents of 22 children in the preterm group and parents of 19 children in the reference group conducted an Ages and Stages Questionnaire (ASQ) when their children had reached the age of 3-3(1/2) y.
Results:
The R-PDQ was easy to use by staff and well accepted by parents. The mean score in the preterm group was 14.9+/-3.9 vs 17.7+/-2.7 in the term group (p<0.001). Three children had developmental scores below-2 SD. The R-PDQ score was associated with the ASQ score 2 y later.
Conclusion:
A structured questionnaire administrated by telephone is an alternative and usable tool for assessing neurodevelopmental deficit in children born extremely preterm. The mean developmental delay in the preterm group compared to the term group (about-1 SD) was close to expectations.
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