Developmental delay at 12 months in children born extremely preterm

Ane Lando1, Anja Klamer, Finn Jonsbo

  • 1Department of Neonatology, Juliane Marie Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark. alando@dadlnet.dk

Insights

A telephone questionnaire effectively assesses neurodevelopmental deficits in extremely preterm infants. This structured tool, the Revised Prescreening Developmental Questionnaire (R-PDQ), proved feasible and valid for early developmental screening.

Area of Science:

  • Neonatal care and developmental pediatrics.
  • Pediatric neurodevelopmental assessment.

Background:

  • Extremely preterm infants (<28 weeks gestation) face risks for neurodevelopmental deficits.
  • Early and accurate assessment is crucial for timely intervention.

Purpose of the Study:

  • To determine the feasibility and validity of a structured telephone interview for assessing neurodevelopment in extremely preterm infants.
  • To compare developmental scores between extremely preterm infants and those born at term.

Main Methods:

  • Parents of 88 extremely preterm infants and 30 term infants were interviewed via telephone at 1 year corrected age using the Revised Prescreening Developmental Questionnaire (R-PDQ).
  • NICU staff conducted the interviews.
  • The R-PDQ's validity was further assessed by comparing its scores with the Ages and Stages Questionnaire (ASQ) at 3-3.5 years.

Main Results:

  • The R-PDQ was user-friendly for staff and well-received by parents.
  • Extremely preterm infants scored significantly lower on the R-PDQ (14.9±3.9) compared to term infants (17.7±2.7), indicating developmental delay.
  • R-PDQ scores correlated with ASQ scores obtained two years later.

Conclusions:

  • A structured telephone questionnaire is a viable and usable method for screening neurodevelopmental deficits in extremely preterm children.
  • The observed mean developmental delay in the preterm group aligns with expected outcomes.
Abstract

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