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Updated: Aug 14, 2026
05:56
Phase-Resolved Functional Lung MRI for Pulmonary Ventilation and Perfusion (V/Q) Assessment
Published on: August 9, 2024
Computed tomography studies of lung ventilation and perfusion
1Department of Radiology, University of Iowa Carver College of Medicine, 200 Hawkins Drive, Iowa City, IA 52240, USA. eric-hoffman@uiowa.edu
Proceedings of the American Thoracic Society
|December 15, 2005
Summary
Multidetector-row computed tomography (CT) enables imaging of lung structure and function. Dynamic CT methods provide detailed regional lung ventilation and perfusion imaging, advancing lung function studies.
Area of Science:
- Pulmonary medicine
- Radiology
- Medical imaging
Background:
- Multidetector-row computed tomography (CT) offers a single modality for imaging lung structure and function.
- Breath-hold spiral CT provides detailed airway, vascular, and lung parenchyma information.
Purpose of the Study:
- To discuss dynamic CT methods for studying regional lung function.
- To highlight advancements in imaging lung ventilation and perfusion.
Main Methods:
- Utilizing stable xenon gas wash-in/wash-out with axial CT for regional ventilation.
- Employing electrocardiogram-gated axial scanning with contrast for regional pulmonary perfusion.
- Achieving isotropic voxel dimensions of approximately 0.4 mm for detailed imaging.
Main Results:
- Dynamic CT methods allow detailed visualization of regional lung ventilation.
- Dynamic CT methods enable detailed visualization of regional pulmonary perfusion.
- These techniques offer high-resolution imaging of lung function heterogeneity.
Conclusions:
- Dynamic CT methods represent a significant advancement in assessing regional lung function.
- These techniques provide a comprehensive approach to understanding lung heterogeneity.
- CT-based functional imaging complements existing methods for lung function assessment.
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