Comparison of motor, cognitive, and behavioral features in progressive supranuclear palsy and Parkinson's disease
Nicholas J Cordato1, Glenda M Halliday, Diana Caine
1Department of Geriatric Medicine, Westmead Hospital and the University of Sydney, Westmead, New South Wales, Australia. nicholas_cordato@wsahs.nsw.gov.au
Abstract:
Major clinical features and global measures were systematically evaluated and compared in progressive supranuclear palsy (PSP) and Parkinson's disease (PD). In addition to gaze palsy and early postural instability in PSP, absence of levodopa-induced dyskinesia, frontalis muscle overactivity, primitive reflexes, visuospatial impairment, and substantial frontal behavioral disturbances differentiated almost all patients with this disorder from PD. For PSP, behavioral changes related to severity of general disability, thereby challenging previous models of relationships between behavior, motor, and cognitive disturbance for this disorder.
Related Concept Videos
Parkinson's Disease: Overview
Parkinson Disease l: Introduction
Parkinson Disease ll: Pathophysiology
Parkinson's Disease: Treatment
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of its...
Neural Regulation
Alterations in Muscle Tone lll


