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Related Experiment Videos

Quantifying regional right ventricular function in tetralogy of Fallot.

Jondavid Menteer1, Paul M Weinberg, Mark A Fogel

  • 1Division of Cardiology, Children's Hospital Los Angeles, MS #34, 4650 Sunset Blvd., Los Angeles, CA 90027, USA. jmenteer@chla.usc.edu

Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance
|December 16, 2005
PubMed
Summary

Quantifying right ventricular (RV) function is challenging. This study shows that 1D myocardial tissue tagging MRI can measure regional RV performance, revealing decreased systolic shortening in tetralogy of Fallot (TOF) patients.

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Area of Science:

  • Cardiovascular Imaging
  • Pediatric Cardiology
  • Cardiac Physiology

Background:

  • Right ventricular (RV) function assessment is complex.
  • Patients with tetralogy of Fallot (TOF) often exhibit impaired RV systolic performance.
  • Accurate regional RV function quantification is crucial for patient management.

Purpose of the Study:

  • To evaluate the utility of 1D myocardial tissue tagging cine-MRI for regional RV performance assessment.
  • To establish normal regional RV shortening ranges.
  • To compare regional RV function in pediatric patients with repaired TOF versus healthy controls.

Main Methods:

  • Utilized 1D myocardial tissue tagging cine-MRI in two views to assess regional RV function.
  • Measured regional systolic shortening in 12 distinct RV segments.

Related Experiment Videos

  • Analyzed data from 32 pediatric patients (21 healthy, 11 with repaired TOF).

    • Main Results:

    • Established normative ranges for regional RV shortening.
    • Demonstrated significantly decreased regional RV shortening in patients with repaired TOF compared to controls.
    • Confirmed region-by-region deficits in RV systolic performance in TOF patients.

    Conclusions:

    • 1D myocardial tissue tagging cine-MRI is a viable technique for measuring regional RV performance.
    • This method effectively identifies and quantifies regional RV systolic dysfunction in pediatric patients with repaired TOF.
    • Findings support the use of this technique for improved assessment of RV function in congenital heart disease.