Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Orbscan global pachymetry: analysis of repeated measures.

Han-Bor Fam1, Kooi-Ling Lim, Dan Z Reinstein

  • 1The Eye Institute, Tan Tock Seng Hospital, Singapore.

Optometry and Vision Science : Official Publication of the American Academy of Optometry
|December 17, 2005
PubMed
Summary

The Orbscan II provides repeatable corneal pachymetry measurements, comparable to ultrasound, especially in the central cornea. Repeatability decreases in peripheral areas due to data point limitations.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Heterogeneous Longitudinal Changes in Corneal Epithelial and Stromal Thicknesses in Patients With Very Asymmetric Ectasia: A Case Series.

Eye & contact lens·2026
Same author

Assessing the Visual and Refractive Outcomes of PRESBYOND Laser Blended Vision Treatment in Myopic and Hyperopic Presbyopic Patients in Western Australia.

Journal of refractive surgery (Thorofare, N.J. : 1995)·2026
Same author

Comment on Epithelial Mapping Efficacy for Subclinical Keratoconus Identification.

American journal of ophthalmology·2025
Same author

Reply.

Retina (Philadelphia, Pa.)·2025
Same author

Clinical Management of Vision Degrading Myodesopsia from Vitreous Floaters: Observation vs. Limited Refractive Vitrectomy.

Ophthalmology. Retina·2025
Same author

"Dose" in Femtosecond Lasers: A Matter of Context and Clarity.

Journal of refractive surgery (Thorofare, N.J. : 1995)·2025

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Corneal Topography

Background:

  • Corneal pachymetry is crucial for diagnosing and managing various eye conditions.
  • Accurate and repeatable pachymetry measurements are essential for reliable clinical assessment.
  • The Orbscan II offers hybrid imaging for comprehensive corneal analysis.

Purpose of the Study:

  • To evaluate the repeatability of global corneal pachymetry measurements using the Orbscan II device.
  • To compare the repeatability of central, thinnest point, and global pachymetry readings.

Main Methods:

  • Twenty healthy volunteers underwent five consecutive Orbscan II examinations.
  • Measurements included central, thinnest point, and global pachymetry.
  • Statistical analysis involved calculating mean, standard deviation, range, coefficient of variance, and intraclass correlation coefficient (ICC).

Related Experiment Videos

Main Results:

  • Orbscan II demonstrated high repeatability for central pachymetry (ICC=0.978) and thinnest point pachymetry (ICC=0.973).
  • Global pachymetry showed a coefficient of variance <1.5% within the central 4 mm and <2.5% across the entire cornea.
  • The highest repeatability (±5 microm) was observed within a central 3.0 x 4.0 mm area.

Conclusions:

  • Orbscan II provides repeatable corneal pachymetry readings comparable to ultrasound pachymetry in central and thinnest point areas.
  • A gradual decrease in repeatability occurs towards the peripheral cornea.
  • Potential limitations in peripheral data acquisition may explain the reduced repeatability.