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[Early and long-term results of valve replacement in patients on chronic hemodialysis]

Sumio Miura1, I Kigawa, T Kitamura

  • 1Department of Cardiovascular Surgery, Mitsui Memorial Hospital, Tokyo, Japan.

Kyobu Geka. the Japanese Journal of Thoracic Surgery
|December 20, 2005
PubMed

Insights

Cardiac valve replacement is high-risk for hemodialysis patients. This study found high operative mortality and low long-term survival rates, with significant bleeding and stroke complications.

Area of Science:

  • Cardiology
  • Nephrology
  • Cardiac Surgery

Context:

  • Cardiac valve replacement is a high-risk procedure for patients undergoing hemodialysis.
  • Outcomes of this patient population are often questioned due to increased perioperative and long-term complications.

Purpose:

  • To evaluate the early and long-term outcomes of cardiac valve replacement in hemodialysis patients at a single institution.

Summary:

  • This retrospective study analyzed 41 hemodialysis patients who underwent valve replacement between 1978 and 2004.
  • Bioprosthetic valves were used in 12.2% of cases.
  • The 30-day operative mortality was 17%, with an in-hospital death rate of 22%.
  • Long-term survival rates at 2, 3, 5, and 10 years were 68%, 54%, 49%, and 27%, respectively.
  • Major bleeding and stroke occurred in 41% of patients.

Impact:

  • The findings highlight the significant risks associated with cardiac valve replacement in hemodialysis patients.
  • Results indicate a need for careful patient selection and management strategies to improve outcomes.
  • This data provides valuable insights for clinicians managing this complex patient cohort.

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