Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Protoreaction of protoplasm.

V V Matveev1

  • 1Laboratory of Cell Physiology, Institute of Cytology, Russian Academy of Sciences, Tikhoretsky Ave 4, St. Petersburg 194064, Russia. vladimir.matveev@gmail.com

Cellular and Molecular Biology (Noisy-Le-Grand, France)
|December 20, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Phase analysis of the cardiac cycle in patients with arterial hypertension based on the results of equilibrium radioventriculography].

Klinicheskaia meditsina·2014
Same author

[Dynamics of parameters of 24-hour blood pressure monitoring and spiro-ergometric test in patients with arterial hypertension during treatment with long acting form of nifedipine].

Kardiologiia·2008
Same author

[Changes of spiroergometric parameters in males under 30 years of age with a hypertensive reaction of arterial pressure to graduated exercise].

Terapevticheskii arkhiv·2007
Same author

[Local myocardial contractility in patients with coronary heart disease and chronic heart failure].

Klinicheskaia meditsina·2006
Same author

"Fathers" and "sons" of theories in cell physiology: the membrane theory.

Cellular and molecular biology (Noisy-le-Grand, France)·2005
Same author

[Cell shrinkage during apoptosis is not obligatory. Apoptosis of U937 cells induced by staurosporine and etoposide].

Tsitologiia·2004

The universal cellular reaction (UCR) involves complex, two-phase changes in cell proteins, affecting viscosity, dye binding, and resistance. This ancient, cell-type-independent response highlights fundamental biological mechanisms.

Area of Science:

  • Cell Biology
  • Cytology
  • Biochemistry

Background:

  • The universal cellular reaction (UCR) was extensively studied by Dmitrii Nasonov's scientific school.
  • The UCR represents a fundamental cellular response to diverse external stimuli.
  • Previous work established UCR involves changes in viscosity, dye binding, membrane potential, and resistance.

Purpose of the Study:

  • To briefly describe the universal cellular reaction (UCR) to external actions.
  • To present a new interpretation of the UCR mechanism.
  • To introduce the concept of cell hydrophobicity and Nasonov's physiological standardization.

Main Methods:

  • Review of Nasonov School's research on UCR.
  • Analysis of structural-functional protein transformations.

Related Experiment Videos

  • Introduction of a new mechanistic interpretation and concept of cell hydrophobicity.
  • Main Results:

    • UCR involves uniform protein structural-functional changes across cell types.
    • These changes are independent of the nature of the physical or chemical agent.
    • A potential role for contractile proteins in muscle cell UCR is proposed.

    Conclusions:

    • The UCR is a universal, ancient biological phenomenon of significant importance.
    • Structural-functional protein changes underpin the UCR.
    • The concept of cell hydrophobicity offers new insights into cellular responses.