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Updated: Aug 14, 2026

Breathing-controlled Electrical Stimulation (BreEStim) for Management of Neuropathic Pain and Spasticity
Published on: January 10, 2013
Deep brain stimulation for the alleviation of post-stroke neuropathic pain
Sarah L F Owen1, Alexander L Green, John F Stein
1University Laboratory of Physiology, University of Oxford, Oxford, UK Department of Neurological Surgery, Radcliffe Infirmary, Oxford, UK.
Abstract:
Our aim was to asses the efficacy of deep brain stimulation in post-stroke neuropathic pain. Since 2000, 15 patients with post-stroke intractable neuropathic pain were treated with deep brain stimulation of the periventricular gray area (PVG), sensory thalamus (Ventroposterolateral nucleus-VPL) or both. Pain was assessed using both a visual analogue scale and the McGill's pain questionnaire. VAS scores show a mean improvement of 48.8% (SD 8.6%). However, there is a wide variation between patients. This study demonstrates that it is an effective treatment in 70% of such patients.
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