Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cardiac resynchronization therapy: Part 1--issues before device implantation.

Jeroen J Bax1, Theodore Abraham, S Serge Barold

  • 1Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands. jbax@knoware.nl

Journal of the American College of Cardiology
|December 20, 2005
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sodium zirconium cyclosilicate post hospital discharge to prevent hyperkalaemia: phase 4, randomized CONTINUITY trial.

Clinical kidney journal·2026
Same author

A new and impactful ESC initiative: ESC Eastern Countries Task Force.

European heart journal·2026
Same author

Access to cardiac implantable electronic device therapy in the ESC EuroAsia region: a comparative analysis of implantation activity, infrastructure, and health financing.

European heart journal. Quality of care & clinical outcomes·2026
Same author

Letter to Dr Maria Giulia Bellicini, MD, Brescia, in response to her letter to the editor of our published paper in ESC Heart Failure (online); Worse long-term outcomes in new-onset HFpEF vs HFrEF and HFmrEF: findings from the Stockholm PREFERS study.

ESC heart failure·2026
Same author

Total NT-proBNP in heart failure with preserved vs reduced ejection fraction.

International journal of cardiology·2026
Same author

Subclinical atrial fibrillation and the risk of heart failure: insights from ARTESiA.

European journal of heart failure·2026

Cardiac resynchronization therapy (CRT) improves outcomes for heart failure patients, but not all respond. Echocardiography may help select patients who will benefit most from this advanced treatment.

Area of Science:

  • Cardiology
  • Medical Devices
  • Heart Failure Management

Background:

  • Cardiac resynchronization therapy (CRT) is a key treatment for end-stage heart failure.
  • Extensive data from 4,017 patients across eight randomized trials support CRT's efficacy.
  • Despite benefits, 20-30% of patients do not respond to CRT.

Purpose of the Study:

  • To review clinical and echocardiographic outcomes of large CRT trials.
  • To provide an overview of echocardiographic techniques for assessing left ventricular (LV) dyssynchrony.
  • To discuss the role of LV scar tissue and venous anatomy in patient selection.

Main Methods:

  • Review of data from eight large, randomized trials on CRT.
  • Summary of clinical and echocardiographic end points reported after CRT.

Related Experiment Videos

  • Overview of echocardiographic techniques for LV dyssynchrony assessment.

    • Main Results:

    • CRT improves symptoms, exercise capacity, quality of life, and survival in heart failure patients.
    • CRT reduces hospitalizations for decompensated heart failure.
    • Echocardiography, particularly tissue Doppler imaging, shows potential for identifying CRT responders by assessing dyssynchrony.

    Conclusions:

    • CRT offers significant benefits for selected heart failure patients.
    • Improved patient selection using echocardiographic assessment of dyssynchrony is crucial for optimizing CRT outcomes.
    • Further investigation into LV scar tissue and venous anatomy may enhance CRT candidate selection.