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Related Experiment Video

Updated: Jul 5, 2026

A New Method for Inducing a Depression-Like Behavior in Rats

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

Global prevalence of dementia: a Delphi consensus study.

Cleusa P Ferri¹, Martin Prince, Carol Brayne

¹Section of Epidemiology, Institute of Psychiatry, King's College, London, UK. c.ferri@iop.kcl.ac.uk

Lancet (London, England)

|December 20, 2005

Summary

Alzheimer's disease affects 24.3 million globally, with 4.6 million new cases annually. Dementia prevalence will double by 2040, disproportionately impacting developing nations.

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Area of Science:

Neurology
Epidemiology
Public Health

Background:

Alzheimer's disease is a leading cause of disability worldwide, posing a significant health burden.
Despite its impact, comprehensive global dementia prevalence data remains limited.

Purpose of the Study:

To determine dementia prevalence across all World Health Organization (WHO) global regions.
To provide updated estimates for 2001, 2020, and projections for 2040.

Main Methods:

Utilized the Delphi consensus method with 12 international experts.
Systematic review of published dementia studies informed expert estimates.
Employed UN population data for demographic projections and incidence calculations.

Main Results:

An estimated 24.3 million people live with dementia globally in 2020.
Approximately 4.6 million new dementia cases emerge annually.
Dementia cases are projected to reach 81.1 million by 2040, with a significant rise in developing countries.

Conclusions:

The study provides the most comprehensive current estimates for global dementia prevalence.
Findings are crucial for informing global health policymaking and resource allocation.
Highlights the urgent need for targeted interventions in high-growth regions.