Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Dependence01:17

Drug Dependence

Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not necessarily...
CNS Depressants: Alcohol and Nicotine01:27

CNS Depressants: Alcohol and Nicotine

Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
Drug Control Governance: Regulatory Bodies and Their Impact01:03

Drug Control Governance: Regulatory Bodies and Their Impact

Drug control governance involves the oversight and regulation of pharmaceuticals to ensure their safety and efficacy while preventing illegal drug use and trafficking. Regulatory bodies, including the US Food and Drug Administration (FDA) and the European Union's European Medicines Agency (EMA), play a central role in this process. These agencies evaluate the safety and efficacy of drugs before they can be marketed. They fund clinical trials and assess the benefits and risks associated with a...
Drug Distribution: Overview01:11

Drug Distribution: Overview

Drug distribution within the body is a dynamic process involving the movement of a drug in two directions across various compartments: from the bloodstream into tissues (tissue uptake) and from tissues back into the bloodstream (tissue release or redistribution). This process is passive and primarily driven by two variables: the concentration gradient between the bloodstream and the extravascular tissues and the drug's ability to cross the cell membrane.
Initially, the free drug in the...
Stimulants01:29

Stimulants

Stimulants are substances that enhance neural activity and elevate dopamine levels in the brain, leading to their highly addictive nature. These drugs include cocaine, amphetamines, MDMA, caffeine, and nicotine, each with distinct mechanisms of action and varied health implications.
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Letter to the Editor: Sources of bias and need for caution in interpreting the results of Spoth et al.'s (2017) PROSPER study.

Psychological medicine·2017
Same author

Slow unfolded-state structuring in Acyl-CoA binding protein folding revealed by simulation and experiment.

Journal of the American Chemical Society·2012
Same author

Co-methylated genes in different adipose depots of pig are associated with metabolic, inflammatory and immune processes.

International journal of biological sciences·2012
Same author

Proteomic analysis of clinical isolate of Stenotrophomonas maltophilia with blaNDM-1, blaL1 and blaL2 β-lactamase genes under imipenem treatment.

Journal of proteome research·2012
Same author

Monitoring ceramic hydroxyapatite media degradation using dynamic image analysis and uniaxial confined bulk compression.

Biotechnology journal·2012
Same author

Genome sequence of the first human adenovirus type 14 isolated in China.

Journal of virology·2012

Related Experiment Video

Updated: Jul 23, 2026

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
05:40

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans

Published on: April 28, 2022

Drug 'hot-spots', alcohol availability and violence.

D M Gorman1, Li Zhu, Scott Horel

  • 1Department of Epidemiology and Biostatistics, Texas A&M Health Science Center, USA. gorman@srph.tamushsc.edu

Drug and Alcohol Review
|December 20, 2005
PubMed
Summary

Drug crime density significantly predicts violent crime rates more than alcohol outlet density. This study in Houston highlights the greater impact of illicit drug activity hot spots on neighborhood violence.

More Related Videos

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
05:12

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

Published on: June 23, 2023

Modeling Alcohol Consumption in Rodents Using Two-Bottle Choice Home Cage Drinking and Microstructural Analysis
08:45

Modeling Alcohol Consumption in Rodents Using Two-Bottle Choice Home Cage Drinking and Microstructural Analysis

Published on: November 8, 2024

Related Experiment Videos

Last Updated: Jul 23, 2026

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
05:40

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans

Published on: April 28, 2022

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
05:12

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

Published on: June 23, 2023

Modeling Alcohol Consumption in Rodents Using Two-Bottle Choice Home Cage Drinking and Microstructural Analysis
08:45

Modeling Alcohol Consumption in Rodents Using Two-Bottle Choice Home Cage Drinking and Microstructural Analysis

Published on: November 8, 2024

Area of Science:

  • Criminology
  • Urban Studies
  • Public Health

Background:

  • Previous ecological studies link alcohol outlet density and drug crime 'hot spots' to violence.
  • No prior research has directly compared the impact of alcohol outlets versus drug hot spots on violence rates.

Purpose of the Study:

  • To examine the comparative effects of alcohol outlet density and drug crime density on violent crime rates in Houston, Texas.
  • To determine which factor, alcohol outlets or drug hot spots, is a stronger predictor of neighborhood violence.

Main Methods:

  • Ecological study design using 439 census tracts in Houston, Texas.
  • Data collected on neighborhood socio-structural factors, alcohol outlet density, drug crime density, and violent crime density.
  • Multivariate and spatial statistics, including ordinary least-squares analysis and control for autocorrelated error.

Main Results:

  • Neighborhood socio-structural factors explained 40% of violent crime variability.
  • Alcohol outlet density added 6% explanatory power; drug crime density added 32%.
  • Drug crime density in target and adjacent tracts significantly predicted violent crime; only off-sale alcohol outlet density in the target tract remained significant.

Conclusions:

  • Drug crime density is a stronger predictor of violent crime rates than alcohol outlet density.
  • Findings suggest that interventions targeting drug crime hot spots may be more effective in reducing violence than those solely focused on alcohol outlets.
  • Methodological and policy implications are discussed, acknowledging study limitations.