The comorbidity of migraine and hypertension. A study in a tertiary care headache centre

Maria Pia Prudenzano1, Carlo Monetti, Lucia Merico

  • 1Headache Disorders Centre, Neurological and Psychiatric Sciences Department, University of Bari, Piazza G. Cesare 11, I-70124, Bari, Italy. m.p.prudenzano@neurol.uniba.it

Insights

Hypertension is more common in migraine and tension-type headache (TTH) patients than the general population, possibly due to seeking medical care. TTH patients showed the highest hypertension rates, suggesting vascular links.

Area of Science:

  • Neurology
  • Cardiovascular Medicine

Background:

  • Conflicting literature exists on migraine and hypertension comorbidity.
  • Hypertension prevalence in headache sufferers requires further investigation.

Purpose of the Study:

  • To compare hypertension distribution in migraineurs versus tension-type headache (TTH) patients.
  • To investigate potential links between headache types and hypertension.

Main Methods:

  • Comparative analysis of hypertension prevalence.
  • Inclusion of migraine and TTH patient cohorts.
  • Comparison with general population hypertension rates.

Main Results:

  • Elevated hypertension prevalence observed in both headache groups compared to the general population.
  • Highest hypertension prevalence detected in TTH patients.
  • Potential Berkson's bias noted in medical-seeking populations.

Conclusions:

  • Headache sufferers exhibit higher hypertension rates, potentially influenced by healthcare-seeking behavior.
  • Findings support vascular mechanisms in tension-type headaches.
  • Further research is needed to clarify migraine-hypertension relationship.

Related Concept Videos

Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
Hypertension I: Introduction01:28

Hypertension I: Introduction

Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
Hypertension V: Nursing Management01:23

Hypertension V: Nursing Management

The nursing management of hypertension involves accurately assessing symptoms, making a comprehensive nursing diagnosis, collaborating with patients to set goals, and implementing targeted interventions to mitigate the condition's impact and improve patient well-being.Comprehensive AssessmentThe initial step in nursing care for hypertension involves a thorough patient assessment. It includes evaluating symptoms such as headaches, dizziness, blurred vision, and previous hypertension episodes.
Increased Intracranial Pressure l: Introduction01:14

Increased Intracranial Pressure l: Introduction

Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...