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Published on: November 7, 2018
Risk factors for hospitalization in children with acute diarrhea: a case control study
S Songül Yalçin1, Samil Hizli, Kadriye Yurdakök
1Social Pediatrics Unit, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Insights
Key risk factors for acute diarrhea hospitalization in young children include dehydration, high purging rates, and lack of breastfeeding. Early medical attention and continued breastfeeding are crucial for preventing severe illness in infants and toddlers.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Background:
- Acute diarrhea is a leading cause of childhood illness and hospitalization globally.
- Identifying risk factors for hospitalization is crucial for effective prevention and management strategies.
Purpose of the Study:
- To identify significant risk factors associated with hospitalization in children aged 0-24 months presenting with acute diarrhea.
- To inform clinical practice and public health interventions aimed at reducing pediatric diarrhea-related hospital admissions.
Main Methods:
- A retrospective case-control study was conducted at a Diarrheal Diseases Training and Treatment Center.
- Hospitalized children (cases) were compared with non-hospitalized children (controls) admitted consecutively.
- Data on clinical history and physical examination were collected and analyzed using univariate and multiple logistic regression.
Main Results:
- Univariate analysis indicated higher rates of purging, vomiting, malnutrition, dehydration, fever, and lack of breastfeeding in hospitalized children.
- Multiple logistic regression identified high purging rate (more than 8/day), presence of dehydration, and absence of breastfeeding as statistically significant risk factors for hospitalization.
- Age, sex, height, blood in stool, and duration of diarrhea did not significantly differ between groups.
Conclusions:
- High purging rate, dehydration, and absence of breastfeeding are critical indicators for potential hospitalization in young children with acute diarrhea.
- Mothers should be advised to seek prompt medical care for children exhibiting these symptoms and to maintain breastfeeding up to 24 months.
- Further multi-center studies are recommended to validate these findings and explore other potential risk factors.
Abstract:
To determine the risk factors for hospitalization in 0 to 24-month-old children with acute diarrhea, a retrospective case-control study was done at the Diarrheal Diseases Training and Treatment Center, where all the cases are managed according to World Health Organization (WHO) criteria. For each hospitalized patient, the next two consecutive admissions were enrolled as the control group. Clinical history and detailed physical examination results on admission were obtained from the standard file for all patients. The two groups were found to be similar for age, sex, height, blood in stool, and duration of diarrhea on admission. However, more children in the hospitalized group had high purging rate, frequent vomiting, malnutrition, dehydration and fever, and were not breast-fed on admission compared to the control group in univariate analysis. In multiple logistic regression analysis, only high purging rate, presence of dehydration and absence of breast-feeding on admission were the statistically significant factors. Mothers should be advised to seek early medical attention if the child has high purging rate (more than 8/day) and to continue breast-feeding up to 24 months of age. Multi-center studies with a large number of cases should be done to clarify the possible risk factors for hospitalization in cases with acute diarrhea.
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