[Infectious disease of simian herpes B virus]

The epidemiology and the method of diagnosis were elucidated for simian herpes B virus (SHBV) infection. It is important that usefulness was demonstrated for the methods of DNA diagnosis having high sensitivity and specificity for SHBV and HSV-1, 2 types, and of detectable serological diagnosis for each specific antibody. The methods allowed the final diagnosis of the human infection due to the reactivation of latent SHBV and the HSV infection from human to monkey. These results would be able to become important and fundamental knowledge for the sero-epidemiological analysis of the infectious stile.