Mid-term results of open aortic valvotomy for infants with critical aortic stenosis: seven-year experience including delayed Ross strategy
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Published on: April 1, 2022
Junichi Koizumi1, Kozo Ishino, Masaaki Kawada
1Department of Cardiovascular Surgery, Okayama University Hospital, Okayama, Japan.
Insights
Open aortic valvotomy (OAV) effectively treats critical aortic stenosis in infants, with no deaths and minimal complications. A delayed Ross procedure is a promising option for recurrent stenosis.
Area of Science:
- Cardiology
- Pediatric Surgery
- Cardiac Surgery
Background:
- Critical aortic stenosis (AS) in infants presents a significant therapeutic challenge.
- Open aortic valvotomy (OAV) is a potential intervention for this condition.
Purpose of the Study:
- To report short- and mid-term outcomes of OAV in infants with critical AS.
- To evaluate the efficacy and safety of OAV as an initial treatment.
Main Methods:
- Retrospective analysis of 6 infants undergoing OAV between 1993 and 1996.
- Procedure involved valvular commissurotomy and nodule excision under cardiopulmonary bypass.
- Patient demographics and pre/post-operative hemodynamic data were recorded.
Main Results:
- No early or late mortality was observed.
- Mean aortic pressure gradient significantly decreased post-OAV (79 mmHg to 33 mmHg).
- Three patients required reintervention for recurrent stenosis, with two later undergoing the Ross procedure.
Conclusions:
- OAV is an effective and safe initial treatment for critical AS in infants.
- A strategy of initial OAV followed by a delayed Ross procedure for recurrence shows promise.
- This approach offers a viable therapeutic option for critical AS in this population.
Objectives:
The purpose of this study is to provide short- and mid-term results of open aortic valvotomy (OAV) for patients with critical aortic stenosis (AS).
Methods:
Between December 1993 and June 1996, 6 patients with critical AS underwent an OAV in our unit. Their ages and body weights at operation ranged from 1 to 65 days (median age, 9 days) and from 2.4 to 5.7 kg (median weight, 3.3 kg), respectively. Peak pressure gradient and diameter of the aortic valve ranged from 25 to 111 mmHg (mean value, 79 mmHg) and from 4.6 to 7.5 mm (mean diameter, 6.1 mm), respectively. OAV comprised the valvular commissurotomy and excision of the myxomatous nodules with cardiopulmonary bypass.
Results:
No early or late death occurred. Mean peak pressure gradient across the aortic valve was reduced to 33 mmHg (from 15 to 44 mmHg) with no aortic insufficiency in 2 patients and trivial insufficiency in 4. During the follow-up period of 6 to 9 years, 3 out of 6 patients required no reintervention. The other 3 patients required repeated valvotomy for recurrent stenosis within 0.2 to 1.3 years after the operation. Of these, 2 patients required the Ross procedure at 7 years of age or older, and another at 6 years of age awaits the Ross procedure.
Conclusion:
OAV for critical AS was effective without causing mortality or significant aortic insufficiency. Our current strategy comprising the initial OAV and "delayed Ross procedure" for recurrent stenosis with or without insufficiency is a promising therapeutic option for infants with critical AS.
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