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Updated: Aug 14, 2026

Facile Protocol for the Synthesis of Self-assembling Polyamine-based Peptide Amphiphiles (PPAs) and Related Biomaterials
Published on: June 25, 2018
A comprehensive view of polyamine and histamine metabolism to the light of new technologies
Miguel Angel Medina1, Florencia Correa-Fiz, Carlos Rodríguez-Caso
1Department of Molecular Biology and Biochemistry, Faculty of Sciences, University of Málaga, Spain. medina@uma.es
Abstract:
Polyamines and histamine are biogenic amines with multiple biological roles. In spite of the evidence for the involvement of both polyamines and histamine metabolism impairment in several highly prevalent pathological conditions, multiple questions concerning the molecular processes behind these effects remain to be elucidated. More comprehensive and systemic studies integrating molecular biology, biophysical and bioinformatics tools could contribute to accelerate the advances in this research area. This review is designed to underscore the main questions to be answered in polyamine and histamine research and how these new systemic approaches could help to find these answers.
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