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Updated: Aug 14, 2026

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
Published on: April 7, 2015
Invasive group A streptococcal infection with pancarditis caused by a new emm-type 12 allele of Streptococcus
Gülşen Ozkaya1, Ali Shorbagi, Zekeriya Ulger
1Section of Infectious Diseases Unit, Hacettepe University School of Medicine, Ankara, Turkey. gozkayasahin@yahoo.com
Abstract:
Throughout the 1980s, a progressive increase in the incidence of Streptococcus pyogenes-related invasive infections has occurred. It has been suggested that a host-related immunogenetic background, as well as bacterial virulence factors may play an important role in the outcome of streptococcal infections. Here, we present the first case of pancarditis in the literature caused by direct bacterial invasion due to a new emm-type 12 allele of S. pyogenes in an immunocompetent patient. The pathogenesis of this invasive infection, as well as predictors of poor prognosis are discussed.
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