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Immunochemically based assays for process control.

B Mattiasson1, H Håkanson

  • 1Department of Biotechnology, Lund University, Sweden.

Advances in Biochemical Engineering/Biotechnology
|January 1, 1992
PubMed
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This review covers immunoanalysis for process control, detailing the evolution of non-equilibrium immunoassays from manual to automated systems. Future developments in immunochemistry for biosensors show significant promise for process monitoring applications.

Area of Science:

  • Analytical Chemistry
  • Biotechnology
  • Process Engineering

Background:

  • Immunoassays are crucial for process control.
  • Traditional methods require manual operation.
  • Advancements are needed for automated, efficient analysis.

Purpose of the Study:

  • To review immunoanalysis techniques for process control.
  • To discuss the development of non-equilibrium immunoassays.
  • To explore immunochemistry applications in biosensors.

Main Methods:

  • Review of non-equilibrium immunoassay development.
  • Discussion of flow injection systems (manual and computerized).
  • Exploration of biosensor approaches using immunochemistry.

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Main Results:

  • Significant progress in automated immunoanalysis for process control.
  • Development from manual to fully computerized systems for sample analysis, calibration, and data evaluation.
  • Consideration of antibody reuse and its impact on assay properties.

Conclusions:

  • The field of immunoanalysis for process control has advanced significantly.
  • Computerized systems offer enhanced capabilities for analysis and data handling.
  • Future developments in biosensors and antibody reuse are anticipated.