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Updated: Aug 14, 2026

Erosion Identification in Metacarpophalangeal Joints in Rheumatoid Arthritis using High-Resolution Peripheral Quantitative Computed Tomography
Published on: October 6, 2023
CPPD crystal deposition disease in patients with rheumatoid arthritis
J C Gerster1, P A Varisco, J Kern
1Department of Rheumatology, CHUV, 1011, Lausanne, Switzerland. Jean-Charles.Gerster@chuv.hospvd.ch
Abstract:
The aim of this study was to assess the frequency and the outcome of patients suffering from rheumatoid arthritis in which calcium pyrophosphate dihydrate (CPPD) crystal deposits were found to coexist in synovial fluid analysis. Such association was more frequent than previously believed with CPPD crystals found in 25.8% of 93 patients with rheumatoid arthritis. As a group, a trend toward a worse outcome was suggested by more frequent prostheses of the lower limb.
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