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Updated: Aug 14, 2026

Scale-up Chemical Synthesis of Thermally-activated Delayed Fluorescence Emitters Based on the Dibenzothiophene-S,S-Dioxide Core
Published on: October 24, 2017
Synthesis and characterization of new fluorene-based singlet oxygen sensitizers
Kevin D Belfield1, Claudia C Corredor, Alma R Morales
1Department of Chemistry and College of Optics & Photonics: CREOL & FPCE, University of Central Florida, P.O. Box 162366, Orlando, Florida 32816-2366, USA. kbelfiel@mail.ucf.edu
Abstract:
The synthesis, photophysical characterization, and determination of singlet oxygen quantum yields (Phi(Delta)) for a class of fluorene derivatives with potential application in two-photon photodynamic therapy (PDT) is reported. It has been demonstrated that these compounds possess the ability to generate singlet oxygen (1O2) upon excitation. A photochemical method, using 1,3-diphenylisobenzofuran (DPBF) as 1O2 chemical quencher, was employed to determine the singlet oxygen quantum yields (Phi(Delta)) of the fluorene-based photosensitizers in ethanol. Phi(Delta) values ranged from 0.35 to 0.75. These derivatives may have potential application as two-photon photosensitizers when pumped via two-photon excitation in the near-IR spectral region.
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