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Updated: Aug 2, 2026

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation
Published on: February 28, 2012
[Association of biventricular resynchronizer and implantable cardioverter defibrillator]
Rogelio Robledo Nolasco1, José Constancio Ruiz Soto, Francisco Méndez Espinoza
1Servicio de Hemodinamia y Electrofisiología, Centro Médico Nacional "20 de Noviembre" ISSSTE. rogelio_robledo@hotmail.com
Insights
Combined cardiac resynchronization and implantable cardioverter defibrillator therapy improved heart failure symptoms and function in three Mexican patients. Two patients experienced appropriate ICD discharges, indicating therapy effectiveness for ventricular arrhythmias.
Area of Science:
- Cardiology
- Medical Devices
Background:
- Congestive heart failure (HF) is a significant public health issue, with dilated cardiomyopathy (DCM) patients facing high risks of sudden cardiac death from arrhythmias.
- Cardiac resynchronization therapy (CRT) and implantable cardioverter defibrillator (ICD) therapy are established treatments for specific HF and arrhythmia conditions.
Observation:
- This study reports on the first three patients in Mexico to receive combined CRT and ICD therapy.
- The patients, all male aged 54-65, had varying degrees of HF (NYHA class II-IV) and reduced left ventricular ejection fraction (LVEF) of 25-35%, with two having prior myocardial infarction.
Findings:
- All three patients demonstrated improvement in functional class and LVEF after receiving the combined therapy.
- Two patients experienced appropriate ICD discharges, confirming the device's efficacy in managing ventricular arrhythmias.
Implications:
- Combined CRT-ICD therapy shows promise for managing complex heart failure patients with ventricular arrhythmias.
- This case series highlights the successful application of advanced cardiac device therapy in a Mexican patient cohort.
Abstract:
Congestive heart failure (HF) remains a major and growing public health problem despite recent therapeutical developments. Thirty to sixty percent of patients with dilated cardiomyopathy (DCM) die suddenly from cardiac arrhythmias. Cardiac resynchronization therapy (CRT) and implantable cardioverter defibrillator (ICD) therapy are effective treatments for HF with a wide QRS and for ventricular arrhythmias respectively. Several trials are currently being performer to evaluate the cardiac resynchronization and implantable cardioverter defibrillator therapy with good results. The objective of this paper is to report the first three patients, in Mexico, that have received this combined therapy. In one patient, a three cameral pacemaker was associated with a unicameral ICD and the other two received a device with both functions. Patients were men, aged 63, 65, and 54 years, two of them with previous myocardial infarct and functional class II to IV of the NYHA. Left ventricular ejection fraction was of 25% in two patients and of 35% in the other. All patients improved their functional class and LVFE, two patients presented discharges of the ICD.
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