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Updated: Aug 14, 2026

A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites
Published on: August 8, 2014
[Influence of connective tissue dysplasia on the clinical course of chronic catarrhal gingivitis]
Abstract:
"MASS"- phenotype or dysplasia of the connective tissue has been studied for many years, but it still remains the actual problem in clinical and theoretical medicine. Expansive integration of clinical genetics and molecular biology into the medicine has revealed the most complicated and multistage structure of the pathogenesis of this disease. The aim of our study was focused on the investigation of "MASS" phenotype and its influence on the stomatological disease such as the early stage of periodontitis -- chronic catarrhal gingivitis. Two groups of subjects with chronic catarrhal gingivitis were examined. Subjects in the first group had the chronic catarrhal gingivitis but did not belong to "MASS" phenotype, while the subjects in the second group had the chronic catarrhal gingivitis and belonged to "MASS" phenotype at the same time. Comparing clinical characteristics of these two groups, the clinical course of catarrhal gingivitis among subjects with "MASS" phenotype was characterised by more acute dynamics, weaker response to conventional treatment and more frequent recidives.
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