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Mitral regurgitation: quantification with 16-detector row CT--initial experience.

Hatem Alkadhi¹, Simon Wildermuth, Dominique A Bettex

¹Institute of Diagnostic Radiology, Institute of Anesthesia, Division of Cardiovascular Anesthesia, and Clinic for Cardiovascular Surgery, University Hospital Zurich, Raemistrasse 100, CH-8091 Zurich, Switzerland. hatem.alkadhi@usz.ch

|December 24, 2005

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Retrospectively electrocardiographic-gated multi-detector row CT can visualize mitral regurgitation. This imaging technique enables accurate quantification of mitral regurgitation severity using planimetric measurements of the regurgitant orifice area.

Area of Science:

Cardiovascular imaging
Medical diagnostics
Radiology

Background:

Mitral regurgitation (MR) is a common valvular heart disease.
Accurate quantification of MR severity is crucial for patient management.
Current imaging modalities have limitations in precise MR assessment.

Purpose of the Study:

To evaluate the capability of retrospectively electrocardiographic (ECG)-gated 16-detector row computed tomography (CT) in depicting mitral regurgitation.
To determine if this CT technique can quantify the severity of mitral regurgitation.

Main Methods:

Nineteen patients with MR and 25 controls underwent retrospectively ECG-gated 16-detector row CT.
CT data sets were reconstructed throughout the cardiac cycle.
The regurgitant orifice area was measured using planimetry during systole.

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Main Results:

No regurgitant orifice was detected in patients without MR.
A regurgitant orifice was visualized in all 19 patients with MR.
The CT-measured regurgitant orifice area showed significant correlation with transesophageal echocardiography and ventriculography findings.

Conclusions:

Retrospectively ECG-gated 16-detector row CT can effectively depict mitral regurgitation.
Planimetric measurement of the regurgitant orifice area allows for quantification of MR severity.
This CT technique offers a valuable tool for assessing mitral regurgitation.