Intestinal obstruction complicating Yersinia enterocolitica serotype O:21 infection in an infant

Areej Mufti1, Nawal A Al Kaabi, Steven Z Rubin

  • 1Department of Pathology and Laboratory Medicine, University of Ottawa, Canada.

Insights

Yersinia enterocolitica infection can rarely cause intestinal obstruction. This case highlights a severe presentation in an infant linked to a specific pathogenic strain, Y. enterocolitica O:21.

Area of Science:

  • Pediatric Gastroenterology
  • Infectious Diseases
  • Microbiology

Background:

  • Yersinia enterocolitica (Y. enterocolitica) infections typically cause gastroenteritis.
  • Intestinal obstruction is a rare but serious complication of Y. enterocolitica infection, particularly in infants.

Observation:

  • An 11-month-old infant presented with enterocolitis and subsequent intestinal obstruction.
  • Yersinia enterocolitica serotype O:21 was identified in the patient's stool.
  • This serotype has been previously associated with severe disease manifestations.

Findings:

  • The case demonstrates a link between Y. enterocolitica serotype O:21 and complicated intestinal obstruction in an infant.
  • The clinical presentation suggests a more pathogenic potential for this specific Y. enterocolitica strain.

Implications:

  • Unusual or severe presentations of yersiniosis may indicate infection with more virulent Y. enterocolitica strains.
  • Early recognition of complicated yersiniosis is crucial for timely intervention in pediatric patients.
  • Further research into the pathogenicity of different Y. enterocolitica serotypes is warranted.

Related Concept Videos

Intestinal Obstruction II: Pathophysiology01:07

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
Pyloric Obstruction01:11

Pyloric Obstruction

Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...
Intestinal Obstruction I: Introduction01:29

Intestinal Obstruction I: Introduction

Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...
Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
Cholera01:25

Cholera

Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...