[Ocular infiltration in a patient with Multiple Myeloma]

Area of Science:

• Oncology
• Ophthalmology
• Hematology

Background:

• Multiple Myeloma (MM) is a plasma cell malignancy.
• Ocular and orbital involvement in MM is uncommon but significant.

Observation:

• A patient with Ig G Kappa Multiple Myeloma, stage IIIA with hepatic infiltration, presented with ocular infiltration.
• The initial sign was a rapidly growing subconjunctival mass.
• This led to ophthalmoplegia and increased intraocular pressure due to orbital infiltration.

Findings:

• The case highlights the potential for Multiple Myeloma to manifest with ocular and orbital infiltration.
• Extramedullary plasmacytoma can present as an isolated ocular or orbital mass.
• Ocular infiltration can present as a subconjunctival mass causing ophthalmoplegia and increased intraocular pressure.

Implications:

• Early recognition of ocular signs in MM patients is vital for prompt diagnosis and management.
• Ophthalmologists should consider MM in the differential diagnosis of rapidly growing orbital or subconjunctival masses.
• This case underscores the importance of a multidisciplinary approach in managing complex MM cases with systemic and ocular involvement.