Related Experiment Video
Updated: Aug 14, 2026

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
Published on: February 19, 2021
Reactive sclerosis: hyperintense appearance on T2-weighted magnetic resonance imaging
K Kanberoglu1, F Kantarci, M H Yilmaz
1Istanbul University, Cerrahpasa Medical Faculty, Department of Radiology, Istanbul, Turkey. zkanber@istanbul.edu.tr
Abstract:
Osteosclerosis is defined as increased density of bone on X-ray imaging studies. It is known that osteosclerosis appears hypointense on both T1- and T2-weighted magnetic resonance imaging sequences. In this review, we present our experience in various sclerotic skeletal pathologies that appear hyperintense on T2-weighted magnetic resonance imaging. We emphasize the possible pathophysiological mechanisms that may cause this appearance, such as bone marrow edema and/or composition of newly formed bone.
