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Updated: Aug 14, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
Where are we with postmenopausal hormone therapy in 2005?
Po M Lam1, Tony K H Chung, Christopher Haines
1Department of Obstetrics and Gynecology, Prince of Wales Hospital, Hong Kong SAR, China. lamponmui@cuhk.edu.hk
Abstract:
Recently, two large randomized placebo-controlled studies on long-term postmenopausal hormone replacement therapy, the Heart and Estrogen/progestin Replacement Study (HERS) and the Women's Health Initiative (WHI), have raise a lot of controversies, especially on the cardiovascular aspects. We briefly review these two trials and discuss what we know and do not know about postmenopausal hormone therapy, including the evidence on novel choices such as raloxifene and tibolone.
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