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Updated: Aug 4, 2026

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
Published on: May 31, 2016
Management of calcified lesions in 2004
Ashish Pershad1, Maurice Buchbinder
1Heart and Vascular Center of Arizona, Phoenix, AZ 85006, USA.
Insights
Managing calcified coronary lesions during percutaneous coronary intervention is complex. This review details evidence-based strategies using balloon and atherectomy devices within the drug-eluting stent era to improve outcomes.
Area of Science:
- Interventional Cardiology
- Cardiovascular Medicine
Background:
- Calcified lesions are increasingly common in cardiac catheterization.
- Percutaneous coronary intervention (PCI) on calcified lesions carries higher risks than on non-calcified lesions.
Purpose of the Study:
- To review current management strategies for complex calcified coronary lesions.
- To discuss evidence-based approaches for treating calcified lesions in the drug-eluting stent era.
Main Methods:
- Review of current literature and evidence-based approaches.
- Discussion of adjunctive treatment modalities for calcified lesions.
Main Results:
- Calcified lesions present unique challenges during PCI.
- Balloon-based and atherectomy devices are key adjunctive therapies.
- Optimal treatment selection is crucial for successful PCI in this subset.
Conclusions:
- Effective management of calcified lesions is essential for reducing PCI complications.
- Drug-eluting stents combined with appropriate adjunctive devices improve outcomes.
- Further research may refine treatment algorithms for calcified coronary lesions.
Abstract:
Calcified lesions are encountered with increasing frequency in the catheterization laboratory. Percutaneous coronary interventions of calcified lesions are associated with a higher complication rate than percutaneous intervention on non-calcified lesions. The review focuses on current management strategies in the drug eluting stent era of this complex lesion subset. Evidence based approaches to treat calcified coronary lesions with balloon based and atherectomy devices as adjunctive modalities in the drug eluting stent era are discussed in this article.
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