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Comparative analysis of BMPR2 gene and its mutations in idiopathic pulmonary arterial hypertension

Wai P K Wong1, James A Knowles, Jane H Morse

  • 1Department of Medicine, Columbia Genome Center, Columbia University College of Physicians and Surgeons and New York State Psychiatric Institute, New York, NY 10032, USA.

Chest
|December 24, 2005
PubMed
Abstract

No abstract available in PubMed .

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Receptor tyrosine kinase inhibitors (TKIs) and calcium channel blockers (CCBs) are two critical categories of drugs employed in the treatment of pulmonary artery hypertension (PAH). PAH is a disease that causes high blood pressure in the pulmonary arteries, resulting in chest pain, fatigue, and shortness of breath.
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